Learn about the latest 2025 ADA Guidelines for Inpatient Glycemic Management and best practices for optimizing blood glucose control in hospitalized patients. This comprehensive overview highlights the American Diabetes Association’s updated clinical recommendations for managing hyperglycemia and diabetes in the inpatient setting, including evidence-based approaches to monitoring, individualized insulin therapy, and goal-directed glucose targets. The guidelines emphasize safe implementation of insulin strategies—both IV and subcutaneous basal-bolus regimens—and the importance of standardized care protocols to reduce complications and improve outcomes. With a focus on personalized care and improved inpatient outcomes, these best practices inform clinicians and healthcare teams on effective strategies for controlling glycemia during hospital stays. The use of advanced Inpatient Insulin Management Software and computerized order sets is also highlighted as a key tool in supporting decision-making, reducing errors, and ensuring consistent adherence to recommended protocols.